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李娜，北京大学教授。1988、 1991 和 1994 年先后获北京大学理学学士、硕士和博士学位。 1994-1998 年，北京大学化学学院工作。 1999-2000，美国堪萨斯大学 药化系 CDDR 博士后。2000至今 北京大学化学学院工作。主要从事光学传感新原理、新方法研究。
李娜 博士，教授，博士生导师
分析化学
电话： 62761187 传真： 62751708
电子信箱： lina@pku.edu.cn
教学：
主讲定量化学分析（英语），为教育部2008年度双语教学示范课程
主讲分析化学系列小班讨论课
获2008年北京市教育教学成果一等奖。
2011年北京市高等教育精品教材
出版教材：
1. Quantitative Chemical Analysis(英文). 北京大学出版社，2009 (主编)
（海外发行World Scientific Publishing Co Pte Ltd, 2013）
2. 分析化学I（电子课件）. 北京大学出版社, 2007(主编)
3. 分析化学教程学习指导. 北京大学出版社, 2006 (参编)
4. 分析化学教程 . 北京大学出版社, 2005 (参编)
5. 超越分子前沿.科学出版社，2004 (参译)
研究领域和兴趣：
光学传感新原理、新方法。
主要兴趣为：
基于金属纳米材料光谱（荧光、局域表面等离子体共振吸收/散射）的生物传感，以及生物大分子与小分子的相互作用。
近五年以来发表的主要学术论文：
- Xiaojing Pei, Haoyan Yin, Tiancheng Lai, Junlong Zhang, Feng Liu, and Xiao Xu, Na Li Multiplexed Detection of Attomole Nucleic Acids Using Fluo-rescent Nanoparticle Counting Platform . Anal. Chem., 2018, 90, 1376-1383.
- Guangyu Tao, Yang Chen, Ruoyun Lin, Jiang Zhou, Xiaojing Pei, Feng Liu, Na Li How G-quadruplex topology and loop sequences affect optical properties of DNA-templated silver nanoclusters.Nano Res. 2017, https://doi.org/10.1007/s12274-017-1844-4
- Ruoyun Lin, Guangyu Tao, Yang Chen, Mingxing Chen, Feng Liu, and Na Li*. Constructing a robust fluorescent DNA-stabilized silver nanocluster probe module by attaching a duplex moiety
- Chem. Eur. J., 2017, 23, 10893-10900Wu, Xi, Tian Li, Guangyu Tao, Ruoyun Lin, Xiaojing Pei, Feng Liu, and Na Li. Universal and Enzyme-Free Immunoassay Platform for Biomarker Detection Based on Gold Nanoparticle Enumeration with a Dark-Field Microscope. Analyst, 2017, 142, 4201-4205.
- Tian. Li, Xi Wu, Feng Liu, and Na Li*.Analytical Methods Based on the Light-Scattering of Plasmonic Nanoparticles at the Single Particle Level with Dark-Field Microscopy Imaging. Analyst, 2017, 142, 248-56.
- Chenxi Li, Yixin Li, Yang Chen, Ruoyun Lin, Tian Li, Feng Liu and Na Li* Modulating the DNA strand-displacement kinetics with the one-sided remote toehold design for differentiation of single-base mismatched DNA. RSC Adv., 2016, 6, 74913-74916
- Yang Chen, Guangyu Tao, Ruoyun Lin, Xiaojing Pei, Feng Liu, and Na Li*'Pre-Incubation of Auric Acid with DNA Is Unnecessary for the Formation of DNA-Templated Gold Nanoclusters.Chem.-an Asian J., 2016, 11, 1677-81.
- Tian Li, Xiao Xu, Guoqing Zhang, Ruoyun Lin, Yang Chen, Chenxi Li, Feng Liu, and Na Li* 'Nonamplification Sandwich Assay Platform for Sensitive Nucleic Acid Detection Based on Aunps Enumeration with the Dark-Field Microscope.Anal. Chem., 2016, 88, 4188-91.
- Xiao Xu, tian Li, Zhongxing Xu, Hejia Wei, Ruoyun Lin, Bin Xia, Feng Liu, Na Li* Automatic enumeration of gold nanomaterials at single particle level. Anal. Chem. 2015, 87, 2576–2581
- Hongduan Huang, Hejia Wei, Mingjian Zou, Xiao Xu,Bin Xia*, Feng Liu, Na Li* Modulating fluorescence anisotropy of terminally labeled dsDNA via the interaction between dye and nucleotides for rational design of DNA-recognition based applications. Anal. Chem. 2015, 87, 2748–2754
- Zhenpeng Zhou, Tian Li, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang,* and Na Li* A dual amplification strategy for DNA detection combining bio-barcode assay and metal-enhanced fluorescence modality. Chem. Commun., 2014, 50, 13373 - 13376
- Chenxi Li, Yixin Li, Xiao Xu, Xinyi Wang, Yang Chen, Xiaoda Yang, Feng Liu, and Na Li* Fast and quantitative differentiation of single-base mismatched DNA by initial reaction rate of catalytic hairpin assembly. Biosens. Bioelectron. 2014, 60, 57-63.
- Zhenpeng Zhou, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang, Na Li* A distance-dependent metal-enhanced fluorescence sensing platform based on molecular beacon design. Biosens. Bioelectron. 2014, 52, 367-373
- Xinyi Wang, Mingjian Zou, Hongduan Huang, Yuqian Ren, Limei Li, Xiaoda Yang, Na Li* Gold nanoparticle enhanced fluorescence anisotropy for the assay of single nucleotide polymorphisms (SNPs) based on toehold-mediated strand-displacement reaction. Biosens. Bioelectron. 2013, 41, 569-575
- Xiao Xu, Yang Chen, Hejia Wei, Bin Xia, Feng Liu and Na Li* Counting Bacteria Using Functionalized Gold Nanoparticles as the Light-Scattering Reporter. Anal. Chem. 2012, 84, 9721-9728.
- Mingjian Zou, Yang Chen, Xiao Xu, Hongduan Huang, Feng Liu, Na Li*. The homogeneous Fluorescence Anisotropic Sensing of Salivary Lysozyme Using the 6-carboxyfluorescein-labeled DNA Aptamer.Biosens. Bioelectron. 2012, 32, 148- 154
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发表于 2018-3-22 08:24:11
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