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黄培强,博士,厦门大学化学化工学院化学系教授。1982年本科毕业于厦门大学,1983年留学法国,1984-1987年在法国国家科研中心、天然产物化学研究所攻读博士学位,1987年获法国南巴黎大学博士学位。1988年在中科院上海有机化学研究所从事博士后研究工作。1990年回厦门大学工作,1993年晋升为教授。1998年遴选为博士生导师。1996年获国家杰出青年科学基金。现任英国皇家化学会会士,国际华人有机化学研讨会顾问委员会委员。《有机化学》第六届编委会副主编,以及《Eur. J. Org. Chem.》、《化学学报》、《Sci. China: Chem.》、《Chin J. Chem.》、《Chin. Chem. Lett.》等国内外学术刊物的国际顾问编委会委员或编委。主要从事天然产物全合成和合成方法学研究。发表论文230余篇。所发展的许多有机反应、方法和策略被国际同行采用。领衔主著专著《Efficiency in Natural Product Synthesis》(Wiley, 2018)和《有机人名反应》。教育部面向21世纪教材《有机合成》被多所高校选为研究生教材或参考书,重印十余次,印数超过万册。
黄培强
教授、博士生导师
电话:(0592)2180992 (实验室)
(0592)2182240 (院办)
传真:(0592)2186400
电子邮箱:pqhuang@xmu.edu.cn
个人简历:
博士 ((法国南巴黎大学,1987)
深入学习文凭(法国蒙彼利埃大学)
学士(厦门大学)
博士后(中国科学院上海有机化学研究所)
英国皇家化学会会士
先后获得国家教委霍英东基金、国家杰出青年科学基金、香港求是科技基金会杰出青年学者奖和中国化学会有机化学委员会有机合成创造奖。
研究兴趣:
有机合成方法学,天然产物(生物碱,信息素等)及药物的不对称合成,多样性导向合成,化学生物学。
近期主要代表论著:
- “A New Method for the Construction of the Hydroxylated Tropane Skeleton: Enantioselective Synthesis of (?)-Bao Gong Teng A”, G.-J. Lin, Z. Xiao and P.-Q. Huang*, Chem. Commun. 2011, 47, 1545-1547.
- “Asymmetric Synthesis of 5-Alkyl Tetramates and the Asymmetric Total Synthesis of Marine Natural Product Belamide A”, H.-Q. Lan, J.-L. Ye, A.-E. Wang, P.-Q. Huang*, Chem. Eur. J. 2011, 17, 958-968.
- “Direct, One-pot Sequential Reductive Alkylation of Lactams/Amides with Grignard and Organolithium Reagents via Lactam/Amide Activation”, K.-J. Xiao, J.-M. Luo, K.-Y. Ye, Y. Wang, and P.-Q. Huang*, Angew. Chem., Int. Ed. 2010, 49, 3037-3040. (highlighted by Nature Chem, and Synfacts).
- “A Flexible Approach to 2-Hydroxyalkyl 3-hydroxy-2-pyrrolidinone Derivatives: Concise Asymmetric Syntheses of (+)-1-Epi-Castanospermine and (+)-Castanospermine, and 7-Deoxy-6-epi-castanospermine”, G. Liu, T.-J. Wu, Y.-P. Ruan, P.-Q. Huang* ,Chem. Eur. J. 2010, 16, 5755-5768.
- “Asymmetric Synthesis of the Cytotoxic Marine Natural Product (+)-Awajanomycin and Its C-11 Epimer”, R. Fu, J.-L. Ye, X.-J. Dai, Y.-P. Ruan, P.-Q.Huang*, J. Org. Chem. 2010, 75, 4230-4243.
- “A Concise and Divergent Approach for the Asymmetric Syntheses of Two Pheromone Components of the Fall Webworm Moth”, Y. Du, J.-F. Zheng, L.-J. Jiang, and P.-Q. Huang*, J. Org. Chem. 2010, 75, 4619-4622.
- “NSAID Sulindac and Its Analog Bind RXR? and Inhibit RXR?-Dependent AKT Signaling”, H. Zhou, W. Liu, Y. Su, Z. Wei, J. Liu, S. K. Kolluri, H. Wu, Y.Cao, J.-B. Chen,Y. Wu, T.-D. Yan, X.-H. Cao, W.-W. Gao, A. Molotkov, F.-Q. Jiang, W.-G. Li, B.-Z. Lin, H.-P. Zhang, J.-H. Yu, S.-P. Luo, J.-Z. Zeng, G. Duester, P.-Q. Huang, and X.-K. Zhang*, Cancer Cell 2010, 17, 560-573 (featured article).
- “First Asymmetric Synthesis of Cytotoxic Marine Natural Product Palau’imide”, H.-Q. Lan, P.-Q. Huang, Chem. Commun. 2010, 46, 5319-5321.
- “Studies towards an Enantioselective Total Synthesis of Sarain A: A Concise Asymmetric Construction of the Diazatricyclic Core”, R.-F. Yang, P.-Q. Huang, Chem. Eur. J. 2010, 16, 10319-10322.
- “Efficient and chemoselective alkylation of amines/amino acids using alcohols as alkylating reagents under mild conditions”, C.-P. Xu, Z.-H. Xiao, B.-Q. Zhuo, Y.-H. Wang and P.-Q. Huang*, Chem. Commun. 2010, 41, 7834-7836.
- “Versatile One-pot Reductive Alkylation of Lactams/Amides via Amide Activation: Application to the Concise Syntheses of Bioactive Alkaloids (±)-Bgugaine, (±)-Coniine, (+)-Preussin, and (–)-Cassine”, K.-J. Xiao, Y. Wang, K.-Y. Ye, and P.-Q. Huang*, Chem. Eur. J. 2010, 16, 12792-12796.
- “One-pot Cross-coupling of N-Acyl N,O-Acetals with ?,?-Unsaturated Compounds”, Y.-G. Xiang, X.-W. Wang, X. Zheng*,Y.-P. Ruana and P.-Q. Huang*, Chem. Commun. 2009, 7045-7047.
- “Asymmetric Syntheses and Wnt Signal Inhibitory Activity of Melleumin A and Four Analogues of Melleumins A, B”, J.-M. Luo, C.-F. Dai, and P.-Q. Huang* ,Chem. Asian J. 2009, 4, 328-335.
- “Asymmetric Synthesis of Hydroxylated Pyrrolidines, Piperidines and Related Bioactive Compounds: from N-Acyliminium Chemistry to N-?-Carbanion Chemistry”, P.-Q. Huang, Synlett 2006, 1133-1147. (Account)
- “Asymmetric Synthesis of Five-Membered Ring Heterocycles” in “Asymmetric Synthesis of Nitrogen Heterocycles”, Contributed chapter: P.-Q. Huang, Ed. Royer, J. Wiley-VCH, Weinheim: 2009
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